Purification and properties of the formate-activating enzyme from erythrocytes.

نویسندگان

  • J R BERTINO
  • B SIMMONS
  • D M DONOHUE
چکیده

The demonstration by Lowy and Williams (2) that rabbit erythrocytes can incorporate C4-formate into the C-2 position of purines suggests by analogy with the well studied avian liver system (3) that Nro-formyltetrahydrofolate is the actual “lcarbon” donor. The synthesis of this compound is carried out by the formate-activating enzyme (also called tetrahydrofolate formylase (4, 5)) as shown in Equation 1.

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عنوان ژورنال:
  • The Journal of biological chemistry

دوره 237  شماره 

صفحات  -

تاریخ انتشار 1962